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  immatics biotechnologies Gm new balance damen bH and BioNTech AG have announced that they are moving a novel concept of fully personalized therapeutic cancer vaccines, Glioma Actively Personalized VAccine Consortium (GAPVAC), into the clinic. The German national authority, t nike dunk sb he Paul-Ehrlich-Institute (PEI), has approved the start of a phase 1/2 study, GAPVAC-101, which applies for the first time the concept of treating glioblastoma patients based on drugs designed and manufactured for each patient individually according to specific characteristics of their tumor and immune system.The screening of first patients for the trial has commenced at the University Hospital of Heidelberg, Germany, and the University Hospital of Tuebingen, Germany. The complex manufacturing of dunk low  the personalized vaccines will be performed by the GMP unit of the University of Tuebingen in close cooperation with the 鈥淕MP and Core Services platform鈥?of the German Cancer Consortium (DKTK).GAPVAC is the first EU-funded initiative aimed at  BAHAWALPUR:Reacting to the soaring prices of fruits in Ramazan, residents of Bahawalpur and Sama stanley  Satta have called for a boycott of the edible items to bring down the 'unjust' rates.聽 Con nb balance cerned citizens have launched a movement on social media asking for three-day boycott of buying fruits.The messages, which started circulating on WhatsApp Wednesday night, asked people to boycott the purchase of fruits from June 2 to June 4 in order to bring their prices down to a normal level.In Ramazan, vendors tend to increase prices of essential items whose sale spikes as the demand increases. However, some sellers claim the rise in prices is not man-made but natural as demand increases manifold.Scorching heat: Ice blocks, air coolers for animals in Bahawalpur ZooWhile speaking to The Express Tribune, residents said prices of fruits, vegetabl adidas campus homme es and other items reduce during Ramazan all over the world but in Pakistan, the prices increase to an extent that it becomes impossible for a common man to bu

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  Caladrius Biosciences announces that Caladrius, through its subsidiary, PCT, has entered into a global collaboration with Hitachi Chemical Co., Ltd. (Hitachi Chemical) that includes licensing, development and equity components. Hitachi Chemical is a global conglomerate with a growing franchise in life sciences, including regenerative medicine.As part of the collaboration, Hitachi Chemical has purchased a 19.9% equity interest in PCT for $19 yeezy boost 350 .4 million. Caladrius will retain the remaining 80.1% ownership of PCT. Caladrius intends to use the acquired capital for continued expansion and improvements at PCT in support of commercial product launch readiness as well as for general corporate purposes.In addition, PCT has licensed its cell therapy technology and know-how to Hitachi Ch nike dunk high emical for cell ther yeezy apy manufacturing in certain Asian territories, including Japan, where the Pharmaceuticals and Medical Devices Agency (鈥淧MDA鈥? has introduced more favorable legislation to stimulate the growth o  Superstar Shah Rukh Khan, whose movie My Name Is Khan聽on Sunday clocked seven years since its release, feels sad that the film's plot about the plight of Muslims in the US after 9/11 is still relevant today.The 2010 drama, which also feat ugg fellboots ured actress Kajol stanley , told the story of Rizvan Khan, who embarks on a journey to meet the US President after his son's killing and attempts to change people's perceptions of the religion.Salman Khan responds to SRK 'Pakistani agent' commentsShah Rukh tweeted: "It's kinda sad too that 'My Name  adidas samba hombre Is Khan' is still relevant. But thanks Karan (Johar), Ravi, Kajol, SEL Shibani Niranjan Deepa Jimmy and all cast/crew for a special film."It鈥檚 kinda sad too that MNIK is still relevant.But thx Karan Ravi Kajol SEL Shibani Niranjan Deepa Jimmy & all cast/crew for a special film— Shah Rukh Khan (@iamsrk) February 11, 2017The actor's message, it seems, hints at US President Donald Trump's controversial executive order to temporarily bar entry into the US to r

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  Celgene Corporation and Quanticel Pharmaceuticals, Inc. have announced a definitive share purchase agreement under which Celgene Corporation will acquire Quanticel. Through the agreement, Celgene will have full access to Quanticel's proprietary platform for the single-cell genomic analysis of human cancer, as well as Quanticel's lead programs that target specific epigenetic modifiers to advance Celgene's pipeline of innovative cancer therapies.The acquisition culminates a 2011 strategic alliance between Celgene and Quanticel. Over the course of the three-and-a-half year alliance, Quanticel industrialized its single-cell platform for analysis of tumor cellular c yeezy 500 ontent and applied it to novel target discovery and the generation of high-quality dr nike dunk sb ug candidates. Multiple drug candidates from Quanticel are expected to enter the clinic in early 2016."This acquisition brings in adidas yeezy to Celgene a highly productive, innovative organization deploying a unique platform of high strategic value" said Tom  GROS-ISLET, SAINT LUCIA:West Indies overcame a mini collapse on their way to a series-levelling four-wicket victory in a low-scoring second ODI against Afghanistan in St Luci new balance 991 a on Sunday.Afghanistan struggled against the extra pace and bounce of the home seam attack, making just 135 off 37.3 overs 鈥?the lowest ODI total at the Darren Sammy Stadium.Shai Hope then scored a patient unbeaten 48 to stave off the threat of Afghan leg-spinner Rashid Khan and take the home side across the finish line with more than 10 overs but just four wickets to spare after falling at one stage to 98-5.First T20I: Narine delighted with man-of-the-match performanceChoosing to bat again on the same pitch used for the first match two days earlier, campus adidas beige  the tourists found the West Indies bowlers to be an entirely di newbalance 990 fferent proposition as they adopted a consistent line of short-pitched bowling on the body which exposed the technical inadequacies of most of the Afghan batsmen.Only Gulbadin Naib, who was last out for a

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  Science has been the driving force in the modernization of the world as we know it, yet science as an industry has failed to adequately diversify with the times. While the new digital age offers opportunities to expand interest in and appeal of STEM careers, many barriers still hinder equitable access for all students. Conversations of famous scientists often draw answers such as 鈥淎lbert Einstein鈥?and 鈥淏ill Nye the Science Guy鈥? While accurate references of scientific leaders, the lack of diversity in the public image of scientists can contribute to the lack of diversity in STEM fields.Introducing the 鈥淚 Am A Scientist鈥?initiative, which provides opportunities for students,  dunks specifically those in Junior Hi yeezys gh School and High School, to interact with the science and stori yeezys slide es of today鈥檚 scientists鈥攂reaking down barriers like race, gender, and personal interests.锘縏he program鈥檚 collection of classroom toolkits provide real-life stories of modern scientists, classroom resources, posters , care  KARACHI:The benchmark-100 index surged to close positive for the sixth successive session, as institutional buying and gains in regional markets was enough to instil confidence in investors.Turnover  new balance femme witnessed improvement, hitting a 16-week high with value of shares going as high as Rs10.9 billion.At close on Wednesday, the Pakistan Stock Exchange鈥檚 KSE-100 index rose 0.84% or 263.79 points to end at 31,772.90.Elixir Securities analyst Ali Raza said  adidas sambarose stocks opened higher fol nb lowing recovery in regional markets and sustained gains throughout the day as benchmark index settled 0.8% higher near 31,800.鈥淐ements led the show on institutional buying with Dera Ghazi Khan Cement (DGKC +4.86%) hitting the upper lock, churning second best volumes and contributing most points to the index gains, while Maple Leaf Cement (MLCF +4.56%) and Fauji Cement (FCCL +3.95%) also made it in top five on volumes chart.鈥淪mall and mid-caps were also up on local retail and prop book buying.鈥濃淢eanwhile, exploration a

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  Protagen AGandGeneva Bioinformatics (GeneBio) SA announced a distribution agreement that allows GeneBio to distribute Protagen鈥檚 Modiro, a software tool enabling rapid and automated detection of true post-translational modifications in MS/MS datasets.Under the terms of the agreement, G ciabatte yeezy eneBio will distribute the Modiro package o nike dunk uomo n a global basis; at the same time, GeneBio and Protagen will collaborate closely in order to seamlessly link the Modiro functionalities to G chanclas yeezy eneBio鈥檚 Phenyx software platform for MS data analysis.Post-translational protein modifications modulate the activity of many proteins and the in-depth analysis of these changes is of growing importance in the research and development of new drug candidates.Modiro enables researchers to identify significantly more of these crucial modifications using existing mass-spectrometry data. In addition, the automated identification of PTMs by Modiro significantly reduces time and efforts in protein analyses.Developed in collaboratio  In the wake of the deadliest shooting in US history at a gay nightclub in Orlando, a聽hacker-activist group hacked into pro-Islamic State (IS) Twitter accounts and replaced them聽with聽gay pride messages and links to gay pornography.The pro-IS accounts that were hacked were all renamed "Jacked by a Ghost" and most linked to the CIA's official website.Islamic State claims Afghan American shooter was 'soldier of caliphate'The Anonymous hacker, who goes by the name of WauchulaGhost on Twit adidas samba rose ter, tweeted his successful takeover of the pro-IS account, with an IP address in Oman, and peppered the account with slogans such as "Make love, not war" using hashtags "#MoreSex #LessDeath #ISIS #ISIL #IslamicState".Another #DaeshBag in #Jordan. @hddgfgds1. Remembering the Innocent lives lost. #Orlando #Anonymous # newbalance 990 GhostOfNoNation pic.twitter.com/bgBEVy5yBC— WauchulaG stanley kaufen host 馃懟 (@WauchulaGhost) June 14, 2016On June 12, the hacker account said that Twitter had deleted the accounts after they were hacked

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  Everest Biotech, a manufacturer of high quality novel antibodies for the international research market, announces the launch of its Antibody Creation Grant. Worth up to $100,000, the funding is on offer to research labs around the world before the deadline of 31st July 2010.Everest Biotech has manufactured more than 2000 affinity purified polyclonal antibodies against novel targets for its own catalogue. Soon, its production line could be working for your lab - if you could use between 20 and 100 novel antibodies to advance your research, the nike dunk high  company says.To apply for the grant, applicants need to follow two simple steps: 1. Select 5鈥?0 target proteins for which there is a need for new antibodies and that your lab can characterize. 2. Fill in a short application form a dunk high vailable at http://everestbiotech.com and send it to support@everestbiotech.com.Everest Biotech鈥檚 scientific panel will judge entries. Once the grant is awarded, Everest Biotech鈥檚 team nike air forces 1  will work with you to pick two pepti  In a series of alarming developments around the world, the trend towards greater authoritarianism is, arguably, most significant as it is alarming adidas campus bianche .Turkey鈥檚 president, Recep Tayyip Erdogan, replaced his prime minister with one who is more 鈥榗ompliant鈥?to his drive of con adidas campus nere centrating executive power.Vladimir Putin has successfully used nationalism to tighten his control over Russia and seems to enjoy great popularity. Xi Jinping is regarded as China鈥檚 most powerful leader since Mao Zedong, presiding over a growing number of crucial  adidas campus gr眉n decision-making committees.In the event of a Trump presidency, commentators fear that he could turn out to be an 鈥淎merican Mussolini鈥?Abuse of power is as old as man himself. Leadership involves the use of power, and, as Lord Acton famously warned, 鈥淧ower corrupts and absolute power corrupts absolutely鈥? And yet, the 鈥榠rony鈥? or paradox, is that leaders without power cannot lead.The prominent psychologist David McClelland distinguished three groups of people by t

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  Trenzyme GmbH and Basel based Celonic AG have announced the closure of a license agreement on Celonics CHO-K1 based cell line expression platform SEFEX. Under the terms of the deal, Trenzyme acquires the non-exclusive rights and know-how on this technology to establish high perform jordan ance cell lines for R&D and GMP production purposes for its clients.The SErum Free EXpression technology, SEFEX, is a royalty-free cell line based on CHO-K1 cells. This powerful platform offered by the Swiss CDMO Celonic can be used throughout the entire development ranging from laboratory cultures to production scale.It is robust, highly performant, easy to implement and guarantees maximum productivity, substantial cost savings and scale-up stability for more project safety. As an experienced R&D cell line developer, Trenzyme is looking  new balance 327 f dunk nike high orward to enter a new market by the closure of the licence agreement on Celonics SEFEX technology."We are very happy since the deal enables us to extend our cell lin  KARACHI:Room 227, on the first floor of the male hostel at Aga Khan University Hospital (AKUH), has seen two deaths in the last six years 鈥?one stanley cup  in 2010 and the other on Wednesday night.A second-year BSc nursing student from Aga Khan School of Nursing, W*, was found dead on Thursday morning in Room 227. This was the same room in which a 21-year-old medical student from Chitral was found dead in April 2010, said a guard on campus.AKU student commits suicideThe nursing student, who allegedly hanged himself from the ceiling fan on Wednesday night, hailed from Gilgit and had been studying at AKUH since 2014. He was enrolled in the 2014 batch and would have been graduating in 2018."He was intelligent, passionate and an active student," said a university official, requesting anonymity. W was studying on a 100 per cent scholarship, with a guar new balance 480 anteed job after he completed his studies, said the official. No one ever saw him show signs of depression, the official told The Exp adidas samba ress Tribune.The uni

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  As the world scrambles to find ways to power the future, renewable fuels, such as those made from biomass, are a common answer. Simply growing as much of the same type of biomass as possible, ho dunk nike store wever, is not sustainable and comes at the expense of the land and animals living there. Researchers have now compared ant communities living in different cropping systems and found that higher plant diversity supported more abundant, diverse, and functional ant communities. This research highlights the importance of finding sustainable ways to grow the crops needed to produce eco-friendlier fuel.Despite being a renewable energy source, the use of biofuel is controversial, as growing few, h yeezy slide ighly productive crops for low dunks nike  fuel can lead to biodiversity loss in the cropping systems where biomass is produced. A cropping system refers to the crops, their sequence, and the management practices on a given field.Now, researchers in the US have compared ant communities in different types of bioenergy cropping  ISLAMABAD:There is a need to have small, modular reactors which can be moved around with ease.鈥淭he need is to have small reactors with an output of less than 300 mega watts, as compared to conventional reactors, since they can be transported easily to the required location,鈥?said Dr Ishfaq Ahmad, the former chairman of the Pakistan Atomic Energy Commission (PAEC) while addressing researchers and scientists at the first symposium on small modular reactors (SMRs) organised by Pakistan Nuclear Society at National Centre for Physics.The SMRs are a type of nuclear fission reactor which are small new balance 480 er than conventional reactors, are manufact nb 530 ured at a plant and moved to a site to be fully constructed.Earlier, Pakistan Nuclear Society President Dr Syed Javaid Khurshid said that Pakistan is increasing  stanley cup its capacity of producing nuclear energy, with the share up from 3.6 per cent to 5.7 per cent in just one year.Published in The Express Tribune, February 24th, 2017.

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  MDRNA, Inc. announces the presentation of data highlighting the ability of the UsiRNA construct to significantly minimize off-target effects while maintaining potent RNA Interference (RNAi) activity.Narendra Vaish, Ph.D., MBA, Associate Director, Discovery Research and Pharmaceutical Development, presented the data at the Keystone Symposia on "RNA Silencing: Mechanism, Biology and Application" from January 14 to 19, 2010, Keystone Resort, Keystone, Colorado.UsiRNAs are MDRNA's propr nike dunk ietary constructs in which Unlocked Nucleobase Analogs (UNA) strategically replace ribonucleobases. Placement of UNA in the passenger strand specifically blocks the activity of this strand to function in RNAi, thus decreasing off-target activity. Placement of UNA withi asics sneaker n the guide strand confers greater specificity upon RNAi by inhibiting micro-RNA-like e dunk nike ffects.Using microarray analysis to simultaneously measure the expression levels of more than 30,000 genes, a UNA in the passenger strand reduced the off-tar  DOHA, QATARatar on Sunday announced three days of national mourning after the former Emir Khalifa bin Hamad Al-Thani, who was deposed in a palace coup, died aged 84.The former ruler, the grandfather of the current Emir Tamim bin Hamad Al-Thani, died on Sunday, according to an off stanley kaufen icial statement from the royal palace.Uzbek govt says President Karimov has diedDur nb 530 ing his time as leader from 1972 to 1995, he oversaw the transformation of modern-day Qatar into an energy-rich country -- where the phenomenal wealth from gas an oil exports transformed the tiny Gulf state."His highness father Emir Sheikh Khalifa bin Hamad Al-Thani passed away on the evening of Sunday October 23, 2016, at the age o new balance f 84 years," read the official statement.Beloved golf great Arnold Palmer dies at 87"His highness Sheikh Tamim bin Hamad Al-Thani has ordered public mourning across the country for three days." No further details were given about the circumstances of his death.Among the first officials to respond to

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  Dr Philips (50) has over 25 years of senior management and Board level experience in public and private companies across Europe, the US and Australia. During this time he has accumulated considerable expertise in M&A and licensing deal origination and  af1 execution, which he now brings to the role of CEO of Midatech.Dr Phillips joins Midatech from Healthcare Brands International Ltd (HBI), the UK consumer healthcare company, where he h yeezys slide as been CEO since 2010. Between 2007 and 2012 he served as Non-executive Chairman of Prosonix Ltd, a specialty pharmaceutical company developing respiratory medicines using an innovative particle-engineering technology and approach.Before joining HBI, Dr Phillips was CEO of Vantia Ltd., a pharmaceutical company developing novel, small molecule drugs. Prior to that he founded and served as CEO of Talisker Pharma until its acquisition by EUSA in 2006, upon which he became President o yeezy sneakers f EUSA Pharma Europe and an Executive Board Member EUSA Pharma Inc. Dr Phil  The PML-N Gilgit-Baltistan (G-B) said the federa stanley cup l government was taking steps for granting constitutional rights to the region.Such measures would help the G-B people join the national main ugg boots stream, said a statement issued by the PML-N G-B Central Secretariat.It was the first time in the country's history that centre was taking revolutionary steps to grant constitutional and basic rights to the people of G-B.Publis adidas samba hed in The Express Tribune, March 12th, 2017.