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MDRNA, Inc. announces the presentation of data highlighting the ability of the UsiRNA construct to significantly minimize off-target effects while maintaining potent RNA Interference (RNAi) activity.Narendra Vaish, Ph.D., MBA, Associate Director, Discovery Research and Pharmaceutical Development, presented the data at the Keystone Symposia on "RNA Silencing: Mechanism, Biology and Application" from January 14 to 19, 2010, Keystone Resort, Keystone, Colorado.UsiRNAs are MDRNA's propr
nike dunk ietary constructs in which Unlocked Nucleobase Analogs (UNA) strategically replace ribonucleobases. Placement of UNA in the passenger strand specifically blocks the activity of this strand to function in RNAi, thus decreasing off-target activity. Placement of UNA withi
asics sneaker n the guide strand confers greater specificity upon RNAi by inhibiting micro-RNA-like e
dunk nike ffects.Using microarray analysis to simultaneously measure the expression levels of more than 30,000 genes, a UNA in the passenger strand reduced the off-tar DOHA, QATAR
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atar on Sunday announced three days of national mourning after the former Emir Khalifa bin Hamad Al-Thani, who was deposed in a palace coup, died aged 84.The former ruler, the grandfather of the current Emir Tamim bin Hamad Al-Thani, died on Sunday, according to an off
stanley kaufen icial statement from the royal palace.Uzbek govt says President Karimov has diedDur
nb 530 ing his time as leader from 1972 to 1995, he oversaw the transformation of modern-day Qatar into an energy-rich country -- where the phenomenal wealth from gas an oil exports transformed the tiny Gulf state."His highness father Emir Sheikh Khalifa bin Hamad Al-Thani passed away on the evening of Sunday October 23, 2016, at the age o
new balance f 84 years," read the official statement.Beloved golf great Arnold Palmer dies at 87"His highness Sheikh Tamim bin Hamad Al-Thani has ordered public mourning across the country for three days." No further details were given about the circumstances of his death.Among the first officials to respond to