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Wvhq Bringing back squash: Five Egyptians from top 20 to play in Pakistan
  The discovery was made by a team of scientists le adidas yeezys d by Alexei Morozov, an assistant professor at the Virginia Tech Carilion Research Institute.The mechanism 鈥?a protein called Rap1 鈥?controls L-type calcium channels, which participate in the formation of long-term memories. Previous studies have also linked alterations in these ion channels to certain psychiatric disorders. The discovery of the channels鈥?regulation by Rap1 could help scientists understand the physiological genesis of bipolar disorder and schizophrenia.鈥淧eople with genetic mutations affecting L-type calcium channels have higher rates of bipolar disorder and  nike dunk schizophrenia,鈥?said Morozov. 鈥淭his suggests t air jordan4 hat there might be a relationship between the activation of L-type calcium channels and these psychiatric disorders. Understanding how these ion channels are controlled is the first step to determining how their functioning or malfunctioning affects mental health.鈥滱 single neuron in the brain can have thousands of synapses  KALABAT:A senior UN official has urged Pakistan to resolve the status of more than 2.5 million Afghan refugees living in Pakistan whose registration cards have expired or who remain unregistered.In December, registration cards providing temporary legal stay to more than 1.5 million Afghan refugees expired, and were granted a six-month extension by the government. But Afghans say they are hassled by police for carrying the expired cards, and members of the estimated newbalance 530  one million Afghans w adidas campus nere ho are still unr adidas samba rose egistered also face difficulties with the authorities, aid workers say. The issue is now before Pakistan's cabinet.UNHCR Assistant High Commissioner George Okoth-Obbo said his agency was engaged in 鈥榗ontinuing discussions鈥?with the Pakistani government to resolve the population's uncertain situation."We await with a lot of interest the decision of the government on those questions," Okoth-Obbo told Reuters during a Friday visit to Khyber-Pakhtunkhwa.Since 2009, international donors have p

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Kgxm Death penalty : A convict executed, another gets a lifeline
ISLAMABAD:The Islamabad High Court on Friday issued a notice to the Pakistan Muslim League-Nawaz (PML-N) on a plea seeking court directives to summon from the Supreme Court registrar records of undertakings and affidavits submitted by the prime minister and the Punjab chief minister before they went into exile.IHC judge Noorul Haq N Qureshi issued the notice to the ruling party for May 19 on an application of Pakistan Muslim League-Q chief Chaudhry Shujaat Hussain.The PML-Q chief has contended that the documents, undertaki adidas campus homme ngs and all other agreements among th new balance grise e incumbent prime minister, the Musharraf government, and Saudi Arabia in 2000 were crucial to resolving issues around PML House in Islamabad, which both parties claim as their property.The PML-Q chief, through his counsel Sardar Abdu boots kaufen l Raziq, said that the petitioner filed an application with the Supreme Court registrar for a copy of the documents but the registrar office refused to entertain on the ground that the petitioner was n BioTek Instruments, a global leader in microplate instrumentation technology, recently received the '2014 Supplier of the Year' award from Fisher Scientific, part of Thermo Fisher Scientific. The award was presented to BioTek in Phoenix, Arizona at Fisher Scientific鈥檚 annual meeting.Fisher Scientific annually pre yeezy damen sents this award to the supplier that best exemplifies outstanding overall performance and support in a number of categories including percent growth, marketing participation, new product development and on time delivery to help grow Fisher鈥檚 North American business. This prestigious award was presented by David Koi, Senior Vice President, Global Portfolio Management and Lisa Witte, President, Research & Safety Division at Fisher Scientific."Our goal is to ensure that our customers - and our cha yeezy slide nnel partners 鈥?consistently receive outstanding pre- and post-sale customer suppor adidas yeezys t. We are honored that Fisher Scientific would recognize our efforts to reach this goal," commented

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Bjyc Germany train attacker may be of Pakistani origin: authorities
  People living downstream from artisanal gold mining sites in Amazonia, Southeast Asia, China, Mongolia, and sub-Saharan Africa are exposed to methylmercury via fish in streams and rivers polluted by small-scale gold mining operations. But public h nb ealth specialists have long been concerned about more direct exposures to mercury for the miners themselves, who inhale vapors when they burn off mercury they have used to amalgamate gold during the recovery of the precious metal. They also can absorb mercury through their skin as they knead it i nb sneakers 574 nto the soil sediment to amalgamate the gold鈥攁 job Renee Gardner of the Karolins tenis yeezys ka Institute in Sweden says is often given to children.Gardner and Ellen Silbergeld of The Johns Hopkins University led a team of researchers attempting to tease out those direct effects of such inorganic mercury exposures. The team started with surveys of artisanal miners in Brazil who worked with either gold, emeralds, or diamonds. The data gathered covered five encampmen  KARACHI:Muttahida Qaumi Movement (MQM)-London convener Nadeem Nusrat has asked his supporters not to hinder the c nb zapatillas ampaign run by Karachi Mayor Wasim Akhtar.The statement came shortly after supporters of the party reportedly tried to stop the mayor from holding a media talk in Shah Faisal Colony where he had kicked off his 100-day city campaign."[Akhtar] should not include any kind of politics in the development works in the city and should dissociate with the people expelled from the MQM," Nusrat advised the mayor, asking him to stay away fr adidas samba homme om the faction led by Dr Farooq Satt adidas campus 00's ar.The MQM has split into two groups after the August 22 incidents of an incendiary speech by party founder Altaf Hussain.The London group leader reiterated his demand of resignations of the representatives of the party in the Senate and national and Sindh assemblies. He said that since they have dissociated themselves from him, they should also return what they got due to him. "First, they submit their resignation

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Oqft Oil prices tumble on pick-up in drilling, strong dollar
KARACHI:It is universally accepted that urban planning falls under the jurisdiction and mandate of the local government - not so for KarachiUrban planner and Shehri - Citizens for a Better Environment (CBE) member Farhan Anwar said this at a stakeholder workshop, titled 'Defining a Good Local Governance Agenda for Karachi'. The workshop was organised by Shehri-CBE in collaboration with German foundation for liberal politics, Friedrich Naumann Stiftung fur die Freiheit, on Friday.According to Anwar, the governance construct that includes local, provincial and federal governments is dysfunctional. The local government, he said, is so adidas samba damen metimes controlled by the federal and sometimes by the  newbalance 574 provincial government. "Local government in all such tiers has been most affected and never empowered," he said.Anwar said that many of the local government functions are performed at the behest of the provincial government. "There is little autonomy [for] the loca stanley-cup l governments," he said, adding that this Cytokines are chemical messengers that help the body get rid of invading bacteria and viruses, and control inflammation. The body carefully balances cytokines because they help keep the immune system healthy. However, this balance is upset if the immu converse allstar ne system overreacts. A serious infection or a severe burn can unleash a cytokine storm in the body. During the storm鈥攁lso call yeezys kaufen ed cytokine release syndrome (CRS)鈥攖he body produces too many cytokines, leading to life-threatening inflammation.Interleukin-6 (IL-6) is a key cytokine in the storm because it helps to drive the inflammation that da nike dunk donna mages the body. IL-6 delivers its message by fastening to IL-6 receptors within cells, which tells the cells to spread inflammation. Because IL-6 is important in CRS, treatments that block the IL-6 signal can relieve inflammation. However, this blocking tends to be long-lasting, which leads to side effects.Want more breaking news?Subscribe to Technology Networks鈥?daily newsletter, delivering breaking sc

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Eews Scientists adopt new strategy to find Huntington s disease therapies
  Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable鈥攅ventually exhibiting signs of Alzheimer鈥檚 disease not unlike that of many elderly humans. Now,new researchdemonstrates that microglia, the immune cells of the brain, wither away as Alzheimer鈥檚 takes hold in air force  both mice and humans, and that APOE4, a key gene variant implicated in Alzheimer鈥檚, may mediate these changes.鈥淥lder mice, and those with the APOE4 variant, have these exhausted, fatigued immune cells in their brains, and we discovered a similar phenomeno nike store dunk n in human datasets,鈥?says Sohail Tavazoie, the Leon Hess professor at Rockefeller. The team dubbed this new class of exhausted cells TI yeezy slide M, for terminally inflammatory microglia. TIM have lost the ability to efficiently remove plaque from the brain and thus may contribute to Alzheimer鈥檚.Want more breaking news?S  RAWALPINDI:A m newbalance an was shot dead over a monetary dispute in  ugg the Naseerabad area of Rawalpindi on Wednesday. Police said a man, identified as Mehboob, allegedly opened fire at Zahid after they ha adidas campus wei脽 d an exchange of hot words over a monetary issue. Police said Zahid died on the spot. Rescue 1122 staff shifted the body to the district headquarters hospital for medico-legal formalities. The police have registered a murder case and started investigation.Published in The Express Tribune, March 10th, 2016.

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Powc Deconstructing brain systems involved in memory and spatial skills
  FEI and NovAliX have announced a strategic partnership to enable NovAliX to provide commercial cryo-electron microscopy (EM)-based structural analysis services to its customers in the pharmaceutical and biotech industry. NovAliX has integrated a cryo-EM workflow based on a transmission electron microscope (TEM). The collaboration combines application, tr asics gel 1130 aining, and support with on-site personnel from FEI.鈥淭here is a growing demand for structural studies from the pharmaceutical industry, driven by the need for a deeper scientific understanding, and also because of stronger regulatory constraints. In the field of biologics, EM analysis has proven to be capable of delivering critical information for antibody selection, epitope mapping and formulation. As for small molecules research programs, cryo-EM can be uniquely valuable to obtain  nike dunk sb structural informat yeezy foam ion on multi-protein complexes or membrane proteins, which is key to understanding the structure-function relationship,鈥?said Denis Zeyer  ISLAMABAD:The  nb balance executive council of Allama Iqbal Open University (AIOU) has approved postgraduate study plan to streamline admissions, examinations and mailing process of MA, MSc, MPhil and PhD programmes. A website will also be launched which will adidas campus pink  contain all required information regarding postgraduate studies, a spokesperson of the university  stanley online shop said.Published in The Express Tribune, March 15th, 2016.

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Oghw Restek Wins Company of the Year
ISLAMABADakistan will return $6.5 billion external public debt in the next 15 mont adidas samba nere hs alone. This repayment will take the total official debt repayments during the five-year tenure of the PML-N government to a whopping $21 billion.The Ministry of Finance shared these staggering figures with the Senate Standing Committee on Finance and Revenue on Tuesday. The $6.5 billion repayments will be m ugg hausschuhe ade from February this year to June 2018 excluding the interest paid on the principal amount, said the ministry.In three years, Pakistan has taken on $25b in fresh loans鈥淲e have no issues in making these payments,鈥?Federal Secretary Finance Tariq Bajwa said.To a question about possibility of floating yet another international bond, Bajwa said the government would inform the committee about this issue at an appropriate time. The $6.5 billion repayments are only on account of the government debt and do not include publicly guaranteed debt and the pri adidas samba adidas vate sector external debt. From June 2013 to Januar TheTulane Center for Gene Therapy has received a four-year grant of more than $1.75 million from theNational Heart, Lung and Blood Institute of theNational Institutes of Health to study ways that adult stem cells might repair damaged heart tissue."We're excited to receive this funding, which represents our  low dunks nike first major grant to explore the potential of s yeezy foam tem cells to repair heart dam jordan schuhe age," says Darwin Prockop, the center's director. "This is a medical problem of tremendous importance, because heart disease is the leading cause of death of American adults."This year, an estimated 650,000 Americans will have a new heart attack and another 450,000 will have a recurrent attack, according to the American Heart Association. In addition, about five million Americans have chronic heart failure that becomes progressively severe with time.With this grant, Prockop and his team, including William Chilean, a co-principal investigator at the LSU Health Sciences Center, seek to better understand adult s

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Ufyo Turkey says gives US new documents on Gulen extradition request
  A law passed in Japan in 1992 aimed to improve urban air quality by banning vehicles that violated certain emission standards from being registered in designated areas. A new study published in Contemporary Economic P adidas yeezy olicy provides evidence that the intervention reduced emissions, contributing to air quality improvements in metropolitan regions.The law has been controversial because of its expense to owners of non-compliant vehicles and because of its unclear new balance sneaker  benefit. The study suggests that the law led to a 3% to 6% reduction in the monthly average ambient concentration of nitrogen dioxide over more than two decades, yielding benefits equal to about US  nike dunk sb $104 million as a result of reduced mortality from asthma.鈥淛apan's automobile law seems to work well, but to formally evaluate the validity of the law, full cost-benefit analyses would need to be undertaken,鈥?said corresponding author Shuhei Nishitatano, PhD, of Kwansei Gakuin University.ReferenceHAVE VEHICLE REGISTRATION RESTRICTIONS I  MADRID:Real Madrid maintained a nb 530  one point lead over Barcelona at the top of La Liga as Cristiano Ronaldo was on target in a hard fought 3-1 win at rock bottom Osasuna on Saturday.Earlier, Barca's front three of Lionel Messi, Luis Suarez and N newbalance 574 eymar all struck in a 6-0 thrashing of Alaves.Madrid also have two games in hand on their title rivals.Alaves to face Barcelona in Copa del Rey finalHowever, both games were overshadowed by horrible injuries as Barca's Aleix Vidal suffered a dislocated right ankle that will keep him out for five months and Osasuna's Tano Bonnin a double leg fracture."There is no such a difference [between the sides]. It is true it was the leader against last in the table, but you h new balance 991 ave to play the games and the opponents always make it difficult against Madrid," said Real boss Zinedine Zidane. "We have to suffer, but in the end we got what we came for."Real extend La Liga lead with 3-0 win over SociedadBarca's success was also soured by violent clashes between fans

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Imyj Talking politics:  Coming months crucial for political environment
  Despite similar rates of enrollment into medical c adidas yeezys are, youth with HIV have much lower rates of viral suppression 鈥?reducing HIV to undetectable level yeezy slide s 鈥?compared to adults, according to an analysis funded by the National Institutes of Health. Among more than 1,000 youth, most of whom were newly enrolled in care at treatment centers throughout the United States, 12% had attained viral suppression, far lower than the 32% to 63% observed in studies of adults over age 24. The findings suggest that after they enroll in an HIV treatment program, a low proportion of youth adhere to care regimens. The study appears in the Journal of Acquired Immune Deficiency Syndromes.鈥淥ur findings indicate an urgency for research on how best to tailor HIV intervention services to the  dunk nike store needs of youth,鈥?said the study鈥檚 first author, Bill G. Kapogiannis, M.D., of the Maternal and Pediatric Infectious Diseases Branch at NIH鈥檚 Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)  PARIS:A massive ice block nearly 100 times the area of Manhattan is poised to break off Antarctica's Larsen C ice shelf, scientists reported Friday.A slow-progressing rift suddenly grew by 18 kilometres (11 miles) at th stanley-cup e end of December, leaving the finger-shaped chunk -- 350 metres thick -- connected along only a small fraction of its length.The rift has also widened, from less than 50 metres (160 feet) in 2011 to nearly 500 metres today."If it doesn't go in the next few months, I'll be amazed," said Adrian Luckman, a professor at Swansea University in Wales, and leader of Britain's Project Midas, which tracks changes in West Antarctic ice formations.Scientists launch unprecedented Antarctic research missionBy itself, the soon-to-be iceberg will not add to sea levels, the likely consequence of ice sheet disintegration that most worries scientists.The real danger is from inland campus adidas  glaciers,  adidas campus 00s held in place by the floating, cliff-like ice shelves that straddle land and sea.The fragile West A

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Hyce Airblue flight escapes accident as tyre bursts during landing
  In a small study of adults with major depression, Johns Hopkins Medicine researchers report that two doses of the psychedelic substance psilocybin, given with supportive psychotherapy, produced rapid and large reductions in depressive symptoms, with most participants showing improvement and hal converse chucks f of study participants achieving remission through the four-week follow-up.A compound found in so-called magic mushrooms, psilocybin produces visual and auditory hallucinations and profound changes in consciousness over a few hours after ingestion. In 2016, Johns Hopkins Medicine researchers first reported that treatment with psilocybin under psychologically supported conditions significantly relieved existential anxiety and depression in people with alife-threatening cancer diagnosis.Now, the new balance 990  findings from the new study, publis asics gel hed Nov. 4 inJAMA Psychiatry, suggest that psilocybin may be effective in the much wider population of patients who suffer from major depression than previously appreciat  LAHORE:The Punjab government has suspended the secretaries of 17 union councils (UCs) for not showing interest in census duties on the first day of the population count.The Punjab Local Government and Community Development (LGCD) also issued s adidas samba nera how-cause notices to three more UC secretaries for remaining absent or leaving their duties early.The official orders available with The Express Tribune show the government has suspended UC-102 secretary Tahir Tanveer, UC-107 secr adidas samba adidas etary Mehmood Butt, UC-113 secretaries Muhammad Rafiq and Muhammad Yasir, UC-124 secretaries Shahbaz Butt and Muhammad Qasim Azeem, UC-185 secretary Mushtaq Raza Bhatti, UC-109 secretary Shahbaz Aziz, UC-106 secreta adidas campus grigie ry Muhammad Abbas, UC-240 secretaries Muhammad Qasim Shah and Muhammad Adeel, UC-68 secretary Mehar Muhammad Afzal, UC-3 secretary Sikandar Hayat, UC-269 secretaries Muhammad Mansha and Muhammad Arshad, UC-140 secretary Tariq Mahmood and UC-58 secretary Qamar Javed. Show-cause notices were issued for UC-114 sec